Tart Cherry Extract — Supplements

Anthocyanin-rich extract with anti-inflammatory, uric acid-lowering, and sleep-promoting properties.

Overview

Tart cherry (Prunus cerasus) extract is rich in anthocyanins and polyphenols that inhibit COX-1 and COX-2 enzymes, reduce inflammatory markers, and lower serum uric acid levels. Clinical trials demonstrate efficacy for exercise-induced muscle soreness reduction, gout flare prevention, sleep quality improvement (via natural melatonin content), and post-exercise recovery. The anti-inflammatory potency is attributed to the unique anthocyanin profile including cyanidin-3-glucosylrutinoside.

Indications

  • Exercise-induced muscle soreness reduction
  • Gout and uric acid management
  • Sleep quality improvement
  • Post-exercise recovery acceleration

Mechanism of Action

Anthocyanins inhibit cyclooxygenase-1 and -2 enzymes, reducing prostaglandin-mediated inflammation

Dosing

CompoundDoseFrequencyNotes
Tart Cherry Extract480 mgOnce dailyStandardized to anthocyanin content; or 30 mL concentrate equivalent

Safety & Contraindications

  • Generally well tolerated; mild GI effects possible
  • Significant sugar content in juice form; choose extract or concentrate
  • May interact with anticoagulants (mild antiplatelet effects)
  • Natural melatonin content may cause drowsiness; avoid before driving