Autologous Secretome for Post-Procedure Healing & Skin Rejuvenation — Skin & Hair
Personalized stem cell secretome derived from your own hair follicles for accelerated healing after laser resurfacing, microneedling, and skin rejuvenation.
Overview
Autologous secretome therapy (Acorn Personalized Secretome Treatment) is a cutting-edge regenerative approach that harnesses bioactive molecules secreted by your own stem cells. Unlike exosomes (which contain only extracellular vesicles), secretomes contain a comprehensive array of growth factors, cytokines, and regenerative proteins at levels up to 34x higher than PRP. The process involves non-invasive collection of approximately 50 hair follicles, from which stem cells are cultured and their nutrient-rich secretome is harvested, lyophilized, and sealed. Before application, the secretome is rehydrated with low molecular weight hyaluronic acid and applied immediately after cosmetic procedures (laser resurfacing, microneedling) in-clinic, then continued at home for up to 2 weeks. Clinical data shows 39% better aesthetic outcomes and 63% better patient satisfaction versus standard care (Aquaphor). This cell-free, autologous product ensures compatibility and eliminates rejection risk.
Indications
- Post-laser resurfacing healing acceleration
- Post-microneedling recovery and optimization
- Skin rejuvenation and anti-aging
- Wound healing and tissue regeneration
- Post-procedure inflammation reduction
- Collagen synthesis and skin barrier restoration
Mechanism of Action
Laser resurfacing or microneedling creates controlled micro-injuries requiring rapid healing and regeneration
Dosing
| Compound | Dose | Frequency | Notes |
|---|---|---|---|
| Autologous Secretome + HA | Apply thin layer to treated area | Immediately post-procedure in clinic, then twice daily at home | Continue for up to 2 weeks post-procedure |
| Autologous Secretome + HA | Apply to face/treatment area | Immediately post-procedure, then once or twice daily | Enhances penetration and healing, use for 7-14 days |
| Autologous Secretome + HA | Apply to clean skin | Once daily (evening preferred) | Can be used independently for anti-aging maintenance |
Evidence Grade
GRADE C
Safety & Contraindications
- Autologous product derived from your own cells - minimal rejection risk
- Cell-free formulation ensures safety and compatibility
- Generally well-tolerated with no known systemic side effects
- Requires professional hair follicle collection in clinical setting
- Product must be properly stored (lyophilized) and rehydrated before use
- Follow provider instructions for post-procedure application timing
- Suitable for all skin types (personalized to individual biology)
- Discontinue if unexpected irritation or allergic reaction occurs