Probiotics Multi-Strain — Supplements
Multi-strain probiotic formulation supporting gut microbiome diversity and immune function.
Overview
Multi-strain probiotics provide a diverse consortium of beneficial bacteria (typically Lactobacillus, Bifidobacterium, and Saccharomyces species) to support gut microbiome composition and function. Meta-analyses of RCTs demonstrate efficacy for antibiotic-associated diarrhea prevention (NNT=13), IBS symptom improvement, and reduced incidence of upper respiratory tract infections. Effects are strain-specific and dose-dependent, with higher CFU counts (>50 billion) and greater strain diversity generally showing stronger clinical outcomes.
Indications
- Antibiotic-associated diarrhea prevention
- IBS symptom management
- Gut microbiome diversity restoration
- Immune function support
- Post-infectious gastroenteritis recovery
Mechanism of Action
Probiotic bacteria compete with pathogens for mucosal adhesion sites and nutrients
Dosing
| Compound | Dose | Frequency | Notes |
|---|---|---|---|
| Probiotics (Multi-Strain) | 50 billion CFU | Once daily | Take with or without food; separate from antibiotics by 2 hours |
Safety & Contraindications
- Gas and bloating may increase initially (typically resolves in 1-2 weeks)
- Avoid in severely immunocompromised patients (risk of bacteremia/fungemia)
- Strain-specific effects; not all probiotics are interchangeable
- Store per manufacturer recommendations (refrigerated vs. shelf-stable)