Aged Garlic Extract — Supplements
Organosulfur-rich garlic preparation with demonstrated cardiovascular and immune benefits.
Overview
Aged garlic extract (AGE) is produced through prolonged aging of raw garlic, converting harsh organosulfur compounds into stable, bioavailable forms such as S-allylcysteine (SAC). AGE has demonstrated cardioprotective effects including reduction in coronary artery calcium progression, blood pressure lowering, and improvement in lipid profiles. Multiple randomized controlled trials support its role in cardiovascular risk reduction and immune modulation.
Indications
- Cardiovascular risk reduction
- Blood pressure management
- Immune system support
- Lipid profile optimization
Mechanism of Action
Aging process converts allicin to stable S-allylcysteine and other bioactive compounds
Dosing
| Compound | Dose | Frequency | Notes |
|---|---|---|---|
| Aged Garlic Extract | 600 mg | Once daily | Standardized to S-allylcysteine content |
| Aged Garlic Extract | 1,200 mg | Once daily | Higher dose for cardiovascular indications |
Safety & Contraindications
- May increase bleeding risk; use caution with anticoagulants
- Potential interaction with CYP3A4-metabolized medications
- Discontinue 7-10 days before elective surgery
- GI discomfort may occur at higher doses