Oxytocin — Neuropeptide hormone

Binds oxytocin receptors (OXTR) in brain and peripheral tissues. Centrally: modulates social bonding, trust, anxiety reduction, and stress response (HPA axis attenuation). Peripherally: uterine contraction, milk ejection, and cardiovascular protection.

Overview

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Compound Class

Neuropeptide hormone

Mechanism of Action

Binds oxytocin receptors (OXTR) in brain and peripheral tissues. Centrally: modulates social bonding, trust, anxiety reduction, and stress response (HPA axis attenuation). Peripherally: uterine contraction, milk ejection, and cardiovascular protection.

Regulatory Status

FDA approved (Pitocin for labor induction/augmentation)

Evidence Level

High (obstetric); Moderate (behavioral/psychiatric off-label)