Nandrolone — Anabolic-Androgenic Steroid (AAS) — 19-nortestosterone derivative
Binds androgen receptors with high anabolic:androgenic ratio (~10:1). Promotes nitrogen retention, collagen synthesis, and bone mineral density. Does not convert to DHT via 5α-reductase (converts to weaker DHN). Aromatizes weakly to estradiol.
Overview
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Compound Class
Anabolic-Androgenic Steroid (AAS) — 19-nortestosterone derivative
Mechanism of Action
Binds androgen receptors with high anabolic:androgenic ratio (~10:1). Promotes nitrogen retention, collagen synthesis, and bone mineral density. Does not convert to DHT via 5α-reductase (converts to weaker DHN). Aromatizes weakly to estradiol.
Regulatory Status
FDA approved (Schedule III controlled substance)
Evidence Level
Moderate-High — FDA-approved for anemia; off-label use has extensive clinical literature