Chonluten — Khavinson bioregulator — bronchial / pulmonary

Chonluten (AEDG sequence, same as Epithalon structurally but bronchial origin) targets lung tissue. In vitro THP-1 monocyte study: inhibited TNF and IL-6 production in LPS-stimulated cells, increased tyrosine phosphorylation of mitogen-activated kinases. Clinical study (n=47, chronic bronchitis with asthmatic component): 82% of patients showed improved health status, reduced coughing, decreased sputum, and disappearance of wheezing.

Overview

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Compound Class

Khavinson bioregulator — bronchial / pulmonary

Mechanism of Action

Chonluten (AEDG sequence, same as Epithalon structurally but bronchial origin) targets lung tissue. In vitro THP-1 monocyte study: inhibited TNF and IL-6 production in LPS-stimulated cells, increased tyrosine phosphorylation of mitogen-activated kinases. Clinical study (n=47, chronic bronchitis with asthmatic component): 82% of patients showed improved health status, reduced coughing, decreased sputum, and disappearance of wheezing.

Regulatory Status

Not FDA approved. Registered pharmaceutical in Russia.

Evidence Level

Low — in vitro data + n=47 small clinical study. Registered pharmaceutical in Russia (Chonluten oral capsules).